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Antiproliferative and apoptotic effects of xanthohumol in cholangiocarcinoma

Cholangiocarcinoma remains the second most prevalent hepatic neoplasm in the United States with a 5-year survival rate of less than 10%. Currently, no systemic therapy has demonstrated efficacy. Therefore, an urgent need for the identification of molecularly targeted compound(s) remains. The Notch s...

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Detalles Bibliográficos
Autores principales: Walden, Daniel, Kunnimalaiyaan, Selvi, Sokolowski, Kevin, Clark, T. Gamblin, Kunnimalaiyaan, Muthusamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675694/
https://www.ncbi.nlm.nih.gov/pubmed/29152142
http://dx.doi.org/10.18632/oncotarget.21422