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Chibby 1: a new component of β-catenin-signaling in chronic myeloid leukemia

Chibby 1 (CBY1) is a small and evolutionarily conserved protein, which act as β-catenin antagonist. CBY1 is encoded by C22orf2 (22q13.1) Its antagonistic function on β-catenin involves the direct interaction with: The C-terminal activation domain of β-catenin, which hinders β-catenin binding with Tc...

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Detalles Bibliográficos
Autores principales: Mancini, Manuela, Soverini, Simona, Gugliotta, Gabriele, Santucci, Maria Alessandra, Rosti, Gianantonio, Cavo, Michele, Martinelli, Giovanni, Castagnetti, Fausto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675707/
https://www.ncbi.nlm.nih.gov/pubmed/29152155
http://dx.doi.org/10.18632/oncotarget.21166