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Chibby 1: a new component of β-catenin-signaling in chronic myeloid leukemia
Chibby 1 (CBY1) is a small and evolutionarily conserved protein, which act as β-catenin antagonist. CBY1 is encoded by C22orf2 (22q13.1) Its antagonistic function on β-catenin involves the direct interaction with: The C-terminal activation domain of β-catenin, which hinders β-catenin binding with Tc...
Autores principales: | Mancini, Manuela, Soverini, Simona, Gugliotta, Gabriele, Santucci, Maria Alessandra, Rosti, Gianantonio, Cavo, Michele, Martinelli, Giovanni, Castagnetti, Fausto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675707/ https://www.ncbi.nlm.nih.gov/pubmed/29152155 http://dx.doi.org/10.18632/oncotarget.21166 |
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