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MYCN Amplification Is Associated with Repressed Cellular Immunity in Neuroblastoma: An In Silico Immunological Analysis of TARGET Database

PURPOSE: RNA and DNA sequencing data are traditionally used to discern intrinsic cellular pathways in cancer pathogenesis, their utility for investigating the tumor microenvironment (TME) has not been fully explored. This study explores the use of sequencing data to investigate immunity within the T...

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Detalles Bibliográficos
Autores principales: Zhang, Peng, Wu, Xiaofang, Basu, Moushumi, Dong, Chen, Zheng, Pan, Liu, Yang, Sandler, Anthony David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675839/
https://www.ncbi.nlm.nih.gov/pubmed/29163537
http://dx.doi.org/10.3389/fimmu.2017.01473