Innate B-1 B Cells Are Not Enriched in Red Blood Cell Autoimmune Mice: Importance of B Cell Receptor Transgenic Selection

Autoimmune hemolytic anemia (AIHA) results from breakdown of humoral tolerance to RBC antigens. Past analyses of B-cell receptor transgenic (BCR-Tg) mice that recognize RBC autoantigens led to a paradigm in which autoreactive conventional B-2 B cells are deleted whereas extramedullary B-1 B cells es...

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Detalles Bibliográficos
Autores principales: Richards, Amanda L., Howie, Heather L., Kapp, Linda M., Hendrickson, Jeanne E., Zimring, James C., Hudson, Krystalyn E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675845/
https://www.ncbi.nlm.nih.gov/pubmed/29163471
http://dx.doi.org/10.3389/fimmu.2017.01366

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675845/
https://www.ncbi.nlm.nih.gov/pubmed/29163471
http://dx.doi.org/10.3389/fimmu.2017.01366

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