Intermediate Latency-Evoked Potentials of Multimodal Cortical Vestibular Areas: Galvanic Stimulation
INTRODUCTION: Human multimodal vestibular cortical regions are bilaterally anterior insulae and posterior opercula, where characteristic vestibular-related cortical potentials were previously reported under acoustic otolith stimulation. Galvanic vestibular stimulation likely influences semicircular...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675885/ https://www.ncbi.nlm.nih.gov/pubmed/29163348 http://dx.doi.org/10.3389/fneur.2017.00587 |
_version_ | 1783276979677560832 |
---|---|
author | Kammermeier, Stefan Singh, Arun Bötzel, Kai |
author_facet | Kammermeier, Stefan Singh, Arun Bötzel, Kai |
author_sort | Kammermeier, Stefan |
collection | PubMed |
description | INTRODUCTION: Human multimodal vestibular cortical regions are bilaterally anterior insulae and posterior opercula, where characteristic vestibular-related cortical potentials were previously reported under acoustic otolith stimulation. Galvanic vestibular stimulation likely influences semicircular canals preferentially. Galvanic stimulation was compared to previously established data under acoustic stimulation. METHODS: 14 healthy right-handed subjects, who were also included in the previous acoustic potential study, showed normal acoustic and galvanic vestibular-evoked myogenic potentials. They received 2,000 galvanic binaural bipolar stimuli for each side during EEG recording. RESULTS: Vestibular cortical potentials were found in all 14 subjects and in the pooled data of all subjects (“grand average”) bilaterally. Anterior insula and posterior operculum were activated exclusively under galvanic stimulation at 25, 35, 50, and 80 ms; frontal regions at 30 and 45 ms. Potentials at 70 ms in frontal regions and at 110 ms at all of the involved regions could also be recorded; these events were also found using acoustic stimulation in our previous study. CONCLUSION: Galvanic semicircular canal stimulation evokes specific potentials in addition to those also found with acoustic otolith stimulation in identically located regions of the vestibular cortex. Vestibular cortical regions activate differently by galvanic and acoustic input at the peripheral sensory level. SIGNIFICANCE: Differential effects in vestibular cortical-evoked potentials may see clinical use in specific vertigo disorders. |
format | Online Article Text |
id | pubmed-5675885 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-56758852017-11-21 Intermediate Latency-Evoked Potentials of Multimodal Cortical Vestibular Areas: Galvanic Stimulation Kammermeier, Stefan Singh, Arun Bötzel, Kai Front Neurol Neuroscience INTRODUCTION: Human multimodal vestibular cortical regions are bilaterally anterior insulae and posterior opercula, where characteristic vestibular-related cortical potentials were previously reported under acoustic otolith stimulation. Galvanic vestibular stimulation likely influences semicircular canals preferentially. Galvanic stimulation was compared to previously established data under acoustic stimulation. METHODS: 14 healthy right-handed subjects, who were also included in the previous acoustic potential study, showed normal acoustic and galvanic vestibular-evoked myogenic potentials. They received 2,000 galvanic binaural bipolar stimuli for each side during EEG recording. RESULTS: Vestibular cortical potentials were found in all 14 subjects and in the pooled data of all subjects (“grand average”) bilaterally. Anterior insula and posterior operculum were activated exclusively under galvanic stimulation at 25, 35, 50, and 80 ms; frontal regions at 30 and 45 ms. Potentials at 70 ms in frontal regions and at 110 ms at all of the involved regions could also be recorded; these events were also found using acoustic stimulation in our previous study. CONCLUSION: Galvanic semicircular canal stimulation evokes specific potentials in addition to those also found with acoustic otolith stimulation in identically located regions of the vestibular cortex. Vestibular cortical regions activate differently by galvanic and acoustic input at the peripheral sensory level. SIGNIFICANCE: Differential effects in vestibular cortical-evoked potentials may see clinical use in specific vertigo disorders. Frontiers Media S.A. 2017-11-03 /pmc/articles/PMC5675885/ /pubmed/29163348 http://dx.doi.org/10.3389/fneur.2017.00587 Text en Copyright © 2017 Kammermeier, Singh and Bötzel. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Neuroscience Kammermeier, Stefan Singh, Arun Bötzel, Kai Intermediate Latency-Evoked Potentials of Multimodal Cortical Vestibular Areas: Galvanic Stimulation |
title | Intermediate Latency-Evoked Potentials of Multimodal Cortical Vestibular Areas: Galvanic Stimulation |
title_full | Intermediate Latency-Evoked Potentials of Multimodal Cortical Vestibular Areas: Galvanic Stimulation |
title_fullStr | Intermediate Latency-Evoked Potentials of Multimodal Cortical Vestibular Areas: Galvanic Stimulation |
title_full_unstemmed | Intermediate Latency-Evoked Potentials of Multimodal Cortical Vestibular Areas: Galvanic Stimulation |
title_short | Intermediate Latency-Evoked Potentials of Multimodal Cortical Vestibular Areas: Galvanic Stimulation |
title_sort | intermediate latency-evoked potentials of multimodal cortical vestibular areas: galvanic stimulation |
topic | Neuroscience |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675885/ https://www.ncbi.nlm.nih.gov/pubmed/29163348 http://dx.doi.org/10.3389/fneur.2017.00587 |
work_keys_str_mv | AT kammermeierstefan intermediatelatencyevokedpotentialsofmultimodalcorticalvestibularareasgalvanicstimulation AT singharun intermediatelatencyevokedpotentialsofmultimodalcorticalvestibularareasgalvanicstimulation AT botzelkai intermediatelatencyevokedpotentialsofmultimodalcorticalvestibularareasgalvanicstimulation |