Pyrrolyl Pyrazoline Carbaldehydes as Enoyl-ACP Reductase Inhibitors: Design, Synthesis and Antitubercular Activity

INTRODUCTION: In efforts to develop new antitubercular (anti-TB) compounds, herein we describe cytotoxic evaluation of 15 newly synthesized pyrrolyl pyrazoline carbaldehydes. METHOD & MATERIALS: Surflex-Docking method was used to study binding modes of the compounds at the active site of the enz...

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Detalles Bibliográficos
Autores principales: Dixit, Sheshagiri R., Joshi, Shrinivas D., Kulkarni, Venkatarao H., Jalalpure, Sunil S., Kumbar, Vijay M., Mudaraddi, Tulasigiriyappa Y., Nadagouda, Mallikarjuna N., Aminabhavi, Tejraj M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676022/
https://www.ncbi.nlm.nih.gov/pubmed/29151986
http://dx.doi.org/10.2174/1874104501711010092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676022/
https://www.ncbi.nlm.nih.gov/pubmed/29151986
http://dx.doi.org/10.2174/1874104501711010092

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