MCR-1 Inhibition with Peptide-Conjugated Phosphorodiamidate Morpholino Oligomers Restores Sensitivity to Polymyxin in Escherichia coli

In late 2015, the first example of a transferrable polymyxin resistance mechanism in Gram-negative pathogens, MCR-1, was reported. Since that report, MCR-1 has been described to occur in many Gram-negative pathogens, and the mechanism of MCR-1-mediated resistance was rapidly determined: an ethanolam...

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Detalles Bibliográficos
Autores principales: Daly, Seth M., Sturge, Carolyn R., Felder-Scott, Christina F., Geller, Bruce L., Greenberg, David E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676038/
https://www.ncbi.nlm.nih.gov/pubmed/29114023
http://dx.doi.org/10.1128/mBio.01315-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676038/
https://www.ncbi.nlm.nih.gov/pubmed/29114023
http://dx.doi.org/10.1128/mBio.01315-17

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