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Mechanisms of Surface Antigenic Variation in the Human Pathogenic Fungus Pneumocystis jirovecii

Microbial pathogens commonly escape the human immune system by varying surface proteins. We investigated the mechanisms used for that purpose by Pneumocystis jirovecii. This uncultivable fungus is an obligate pulmonary pathogen that in immunocompromised individuals causes pneumonia, a major life-thr...

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Detalles Bibliográficos
Autores principales: Schmid-Siegert, Emanuel, Richard, Sophie, Luraschi, Amanda, Mühlethaler, Konrad, Pagni, Marco, Hauser, Philippe M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676039/
https://www.ncbi.nlm.nih.gov/pubmed/29114024
http://dx.doi.org/10.1128/mBio.01470-17