Rapid, Selection-Free, High-Efficiency Genome Editing in Protozoan Parasites Using CRISPR-Cas9 Ribonucleoproteins

Trypanosomatids (order Kinetoplastida), including the human pathogens Trypanosoma cruzi (agent of Chagas disease), Trypanosoma brucei, (African sleeping sickness), and Leishmania (leishmaniasis), affect millions of people and animals globally. T. cruzi is considered one of the least studied and most...

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Detalles Bibliográficos
Autores principales: Soares Medeiros, Lia Carolina, South, Lilith, Peng, Duo, Bustamante, Juan M., Wang, Wei, Bunkofske, Molly, Perumal, Natasha, Sanchez-Valdez, Fernando, Tarleton, Rick L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676044/
https://www.ncbi.nlm.nih.gov/pubmed/29114029
http://dx.doi.org/10.1128/mBio.01788-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676044/
https://www.ncbi.nlm.nih.gov/pubmed/29114029
http://dx.doi.org/10.1128/mBio.01788-17

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