Dopamine D4 receptor activation restores CA1 LTP in hippocampal slices from aged mice

Normal aging is characterized with a decline in hippocampal memory functions that is associated with changes in long‐term potentiation (LTP) of the CA3‐to‐CA1 synapse. Age‐related deficit of the dopaminergic system may contribute to impairment of CA1 LTP. Here we assessed how the modulation of CA1 L...

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Detalles Bibliográficos
Autores principales: Guo, Fangli, Zhao, Jianhua, Zhao, Dandan, Wang, Jiangang, Wang, Xiaofang, Feng, Zhiwei, Vreugdenhil, Martin, Lu, Chengbiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676052/
https://www.ncbi.nlm.nih.gov/pubmed/28975698
http://dx.doi.org/10.1111/acel.12666

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676052/
https://www.ncbi.nlm.nih.gov/pubmed/28975698
http://dx.doi.org/10.1111/acel.12666

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