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Hyperphosphatemia induces senescence in human endothelial cells by increasing endothelin‐1 production
Hyperphosphatemia is related to some pathologies, affecting vascular cell behavior. This work analyzes whether high concentration of extracellular phosphate induces endothelial senescence through up‐regulation of endothelin‐1 (ET‐1), exploring the mechanisms involved. The phosphate donor β‐glyceroph...
Autores principales: | Olmos, Gemma, Martínez‐Miguel, Patricia, Alcalde‐Estevez, Elena, Medrano, Diana, Sosa, Patricia, Rodríguez‐Mañas, Leocadio, Naves‐Diaz, Manuel, Rodríguez‐Puyol, Diego, Ruiz‐Torres, María Piedad, López‐Ongil, Susana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676064/ https://www.ncbi.nlm.nih.gov/pubmed/28857396 http://dx.doi.org/10.1111/acel.12664 |
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