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Age‐associated dysregulation of protein metabolism in the mammalian oocyte

Reproductive aging is characterized by a marked decline in oocyte quality that contributes to infertility, miscarriages, and birth defects. This decline is multifactorial, and the underlying mechanisms are under active investigation. Here, we performed RNA‐Seq on individual growing follicles from re...

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Detalles Bibliográficos
Autores principales: Duncan, Francesca E., Jasti, Susmita, Paulson, Ariel, Kelsh, John M., Fegley, Barbara, Gerton, Jennifer L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676066/
https://www.ncbi.nlm.nih.gov/pubmed/28994181
http://dx.doi.org/10.1111/acel.12676