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Genetic interaction with temperature is an important determinant of nematode longevity

As in other poikilotherms, longevity in C. elegans varies inversely with temperature; worms are longer‐lived at lower temperatures. While this observation may seem intuitive based on thermodynamics, the molecular and genetic basis for this phenomenon is not well understood. Several recent reports ha...

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Detalles Bibliográficos
Autores principales: Miller, Hillary, Fletcher, Marissa, Primitivo, Melissa, Leonard, Alison, Sutphin, George L., Rintala, Nicholas, Kaeberlein, Matt, Leiser, Scott F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676069/
https://www.ncbi.nlm.nih.gov/pubmed/28940623
http://dx.doi.org/10.1111/acel.12658