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TOR‐mediated regulation of metabolism in aging

Cellular metabolism is regulated by the mTOR kinase, a key component of the molecular nutrient sensor pathway that plays a central role in cellular survival and aging. The mTOR pathway promotes protein and lipid synthesis and inhibits autophagy, a process known for its contribution to longevity in s...

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Detalles Bibliográficos
Autores principales: Antikainen, Henri, Driscoll, Monica, Haspel, Gal, Dobrowolski, Radek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676073/
https://www.ncbi.nlm.nih.gov/pubmed/28971552
http://dx.doi.org/10.1111/acel.12689