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Recapitulating cortical development with organoid culture in vitro and modeling abnormal spindle-like (ASPM related primary) microcephaly disease

The development of a cerebral organoid culture in vitro offers an opportunity to generate human brain-like organs to investigate mechanisms of human disease that are specific to the neurogenesis of radial glial (RG) and outer radial glial (oRG) cells in the ventricular zone (VZ) and subventricular z...

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Detalles Bibliográficos
Autores principales: Li, Rui, Sun, Le, Fang, Ai, Li, Peng, Wu, Qian, Wang, Xiaoqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676597/
https://www.ncbi.nlm.nih.gov/pubmed/29058117
http://dx.doi.org/10.1007/s13238-017-0479-2