AQP3 is regulated by PPARγ and JNK in hepatic stellate cells carrying PNPLA3 I148M

Aquaglyceroporins (AQPs) allow the movement of glycerol that is required for triglyceride formation in hepatic stellate cells (HSC), as key cellular source of fibrogenesis in the liver. The genetic polymorphism I148M of the patatin-like phospholipase domain-containing 3 (PNPLA3) is associated with h...

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Detalles Bibliográficos
Autores principales: Tardelli, Matteo, Bruschi, Francesca V., Claudel, Thierry, Moreno-Viedma, Veronica, Halilbasic, Emina, Marra, Fabio, Herac, Merima, Stulnig, Thomas M., Trauner, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676689/
https://www.ncbi.nlm.nih.gov/pubmed/29116096
http://dx.doi.org/10.1038/s41598-017-14557-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676689/
https://www.ncbi.nlm.nih.gov/pubmed/29116096
http://dx.doi.org/10.1038/s41598-017-14557-9

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