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The EphB6 receptor is overexpressed in pediatric T cell acute lymphoblastic leukemia and increases its sensitivity to doxorubicin treatment

While impressive improvements have been achieved in T-ALL therapy, current treatment approaches fail in approximately 25% of patients and these patients have limited treatment options. Another significant group of patients is being overtreated, which causes long-lasting side effects. Identification...

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Detalles Bibliográficos
Autores principales: El Zawily, Amr, McEwen, Emily, Toosi, Behzad, Vizeacoumar, Frederick S., Freywald, Tanya, Vizeacoumar, Franco J., Freywald, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676711/
https://www.ncbi.nlm.nih.gov/pubmed/29116180
http://dx.doi.org/10.1038/s41598-017-15200-3