Cargando…
The EphB6 receptor is overexpressed in pediatric T cell acute lymphoblastic leukemia and increases its sensitivity to doxorubicin treatment
While impressive improvements have been achieved in T-ALL therapy, current treatment approaches fail in approximately 25% of patients and these patients have limited treatment options. Another significant group of patients is being overtreated, which causes long-lasting side effects. Identification...
Autores principales: | El Zawily, Amr, McEwen, Emily, Toosi, Behzad, Vizeacoumar, Frederick S., Freywald, Tanya, Vizeacoumar, Franco J., Freywald, Andrew |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676711/ https://www.ncbi.nlm.nih.gov/pubmed/29116180 http://dx.doi.org/10.1038/s41598-017-15200-3 |
Ejemplares similares
-
The intrinsically kinase-inactive EPHB6 receptor predisposes cancer cells to DR5-induced apoptosis by promoting mitochondrial fragmentation
por: El Zawily, Amr M., et al.
Publicado: (2016) -
Targeting synthetic lethality between the SRC kinase and the EPHB6 receptor may benefit cancer treatment
por: Paul, James M., et al.
Publicado: (2016) -
EPHB6 augments both development and drug sensitivity of triple-negative breast cancer tumours
por: Toosi, Behzad M., et al.
Publicado: (2018) -
An integrated computational and experimental study uncovers FUT9 as a metabolic driver of colorectal cancer
por: Auslander, Noam, et al.
Publicado: (2017) -
Protein Tyrosine Kinases: Their Roles and Their Targeting in Leukemia
por: K. Bhanumathy, Kalpana, et al.
Publicado: (2021)