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Comparative evaluation of tumor targeting using the anti-HER2 ADAPT scaffold protein labeled at the C-terminus with indium-111 or technetium-99m

ABD-Derived Affinity Proteins (ADAPTs) is a novel class of engineered scaffold proteins derived from an albumin-binding domain of protein G. The use of ADAPT6 derivatives as targeting moiety have provided excellent preclinical radionuclide imaging of human epidermal growth factor 2 (HER2) tumor xeno...

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Detalles Bibliográficos
Autores principales: Garousi, Javad, Lindbo, Sarah, Mitran, Bogdan, Buijs, Jos, Vorobyeva, Anzhelika, Orlova, Anna, Tolmachev, Vladimir, Hober, Sophia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676751/
https://www.ncbi.nlm.nih.gov/pubmed/29116215
http://dx.doi.org/10.1038/s41598-017-15366-w