A method for measuring the distribution of the shortest telomeres in cells and tissues

Improved methods to measure the shortest (not just average) telomere lengths (TLs) are needed. We developed Telomere Shortest Length Assay (TeSLA), a technique that detects telomeres from all chromosome ends from <1 kb to 18 kb using small amounts of input DNA. TeSLA improves the specificity and...

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Detalles Bibliográficos
Autores principales: Lai, Tsung-Po, Zhang, Ning, Noh, Jungsik, Mender, Ilgen, Tedone, Enzo, Huang, Ejun, Wright, Woodring E., Danuser, Gaudenz, Shay, Jerry W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676791/
https://www.ncbi.nlm.nih.gov/pubmed/29116081
http://dx.doi.org/10.1038/s41467-017-01291-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676791/
https://www.ncbi.nlm.nih.gov/pubmed/29116081
http://dx.doi.org/10.1038/s41467-017-01291-z

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