Targeting autophagy inhibits melanoma growth by enhancing NK cells infiltration in a CCL5-dependent manner

While blocking tumor growth by targeting autophagy is well established, its role on the infiltration of natural killer (NK) cells into tumors remains unknown. Here, we investigate the impact of targeting autophagy gene Beclin1 (BECN1) on the infiltration of NK cells into melanomas. We show that, in...

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Detalles Bibliográficos
Autores principales: Mgrditchian, Takouhie, Arakelian, Tsolere, Paggetti, Jérôme, Noman, Muhammad Zaeem, Viry, Elodie, Moussay, Etienne, Van Moer, Kris, Kreis, Stephanie, Guerin, Coralie, Buart, Stephanie, Robert, Caroline, Borg, Christophe, Vielh, Philippe, Chouaib, Salem, Berchem, Guy, Janji, Bassam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2017
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676879/
https://www.ncbi.nlm.nih.gov/pubmed/29078276
http://dx.doi.org/10.1073/pnas.1703921114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676879/
https://www.ncbi.nlm.nih.gov/pubmed/29078276
http://dx.doi.org/10.1073/pnas.1703921114

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