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Targeting autophagy inhibits melanoma growth by enhancing NK cells infiltration in a CCL5-dependent manner
While blocking tumor growth by targeting autophagy is well established, its role on the infiltration of natural killer (NK) cells into tumors remains unknown. Here, we investigate the impact of targeting autophagy gene Beclin1 (BECN1) on the infiltration of NK cells into melanomas. We show that, in...
Autores principales: | Mgrditchian, Takouhie, Arakelian, Tsolere, Paggetti, Jérôme, Noman, Muhammad Zaeem, Viry, Elodie, Moussay, Etienne, Van Moer, Kris, Kreis, Stephanie, Guerin, Coralie, Buart, Stephanie, Robert, Caroline, Borg, Christophe, Vielh, Philippe, Chouaib, Salem, Berchem, Guy, Janji, Bassam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676879/ https://www.ncbi.nlm.nih.gov/pubmed/29078276 http://dx.doi.org/10.1073/pnas.1703921114 |
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