Cargando…

PTIP chromatin regulator controls development and activation of B cell subsets to license humoral immunity in mice

B cell receptor signaling and downstream NF-κB activity are crucial for the maturation and functionality of all major B cell subsets, yet the molecular players in these signaling events are not fully understood. Here we use several genetically modified mouse models to demonstrate that expression of...

Descripción completa

Detalles Bibliográficos
Autores principales: Su, Dan, Vanhee, Stijn, Soria, Rebeca, Gyllenbäck, Elin Jaensson, Starnes, Linda M., Højfeldt, Martina Kubec, Pedersen, Gabriel K., Yuan, Joan, Daniel, Jeremy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676899/
https://www.ncbi.nlm.nih.gov/pubmed/29078319
http://dx.doi.org/10.1073/pnas.1707938114