Thalidomide Inhibits TGF-β1-induced Epithelial to Mesenchymal Transition in Alveolar Epithelial Cells via Smad-Dependent and Smad-Independent Signaling Pathways

Recent evidence indicates that the epithelial to mesenchymal transition (EMT) in primary alveolar cells (AECs) plays an important role in idiopathic pulmonary fibrosis (IPF). In vivo models have suggested that thalidomide (THL) has anti-fibrotic effects against pulmonary fibrosis, but the underlying...

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Detalles Bibliográficos
Autores principales: Zhou, Xian-Long, Xu, Peng, Chen, Hai-Hua, Zhao, Yan, Shen, Jun, Jiang, Cheng, Jiang, Shan, Ni, Shao-Zhou, Xu, Bing, Li, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5677010/
https://www.ncbi.nlm.nih.gov/pubmed/29116196
http://dx.doi.org/10.1038/s41598-017-15239-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5677010/
https://www.ncbi.nlm.nih.gov/pubmed/29116196
http://dx.doi.org/10.1038/s41598-017-15239-2

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