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The expression of miRNAs is associated with tumour genome instability and predicts the outcome of ovarian cancer patients treated with platinum agents

miRNAs, a class of short but stable noncoding RNA molecules, have been revealed to play important roles in the DNA damage response (DDR). However, their functions in cancer genome instability and the consequent clinical effect as the response to chemotherapy have not been fully elucidated. In this s...

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Detalles Bibliográficos
Autores principales: Wang, Tianzhen, Wang, Guangyu, Zhang, Xiaoxiao, Wu, Di, Yang, Lei, Wang, Guangyou, Hao, Dapeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5677022/
https://www.ncbi.nlm.nih.gov/pubmed/29116111
http://dx.doi.org/10.1038/s41598-017-12259-w