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Convenient iron-catalyzed reductive aminations without hydrogen for selective synthesis of N-methylamines
N-Methylated amines play an important role in regulating the biological and pharmaceutical properties of all kinds of life science molecules. In general, this class of compounds is synthesized via reductive amination reactions using high pressure of molecular hydrogen. Thus, on laboratory scale espe...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5677081/ https://www.ncbi.nlm.nih.gov/pubmed/29116077 http://dx.doi.org/10.1038/s41467-017-01428-0 |