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Convenient iron-catalyzed reductive aminations without hydrogen for selective synthesis of N-methylamines

N-Methylated amines play an important role in regulating the biological and pharmaceutical properties of all kinds of life science molecules. In general, this class of compounds is synthesized via reductive amination reactions using high pressure of molecular hydrogen. Thus, on laboratory scale espe...

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Detalles Bibliográficos
Autores principales: Natte, Kishore, Neumann, Helfried, Jagadeesh, Rajenahally V., Beller, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5677081/
https://www.ncbi.nlm.nih.gov/pubmed/29116077
http://dx.doi.org/10.1038/s41467-017-01428-0