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Thermodynamic cooperativity of cosubstrate binding and cation selectivity of Salmonella typhimurium MelB

The Na(+)-coupled melibiose symporter MelB, which can also be coupled to H(+) or Li(+) transport, is a prototype for the glycoside-pentoside-hexuronide:cation symporter family. Although the 3-D x-ray crystal structure of Salmonella typhimurium MelB (MelB(St)) has been determined, the symport mechani...

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Detalles Bibliográficos
Autores principales: Hariharan, Parameswaran, Guan, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5677108/
https://www.ncbi.nlm.nih.gov/pubmed/29054867
http://dx.doi.org/10.1085/jgp.201711788