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Thermodynamic cooperativity of cosubstrate binding and cation selectivity of Salmonella typhimurium MelB
The Na(+)-coupled melibiose symporter MelB, which can also be coupled to H(+) or Li(+) transport, is a prototype for the glycoside-pentoside-hexuronide:cation symporter family. Although the 3-D x-ray crystal structure of Salmonella typhimurium MelB (MelB(St)) has been determined, the symport mechani...
Autores principales: | Hariharan, Parameswaran, Guan, Lan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5677108/ https://www.ncbi.nlm.nih.gov/pubmed/29054867 http://dx.doi.org/10.1085/jgp.201711788 |
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