Whole Genome Sequence Analysis of Mutations Accumulated in rad27Δ Yeast Strains with Defects in the Processing of Okazaki Fragments Indicates Template-Switching Events

Okazaki fragments that are formed during lagging strand DNA synthesis include an initiating primer consisting of both RNA and DNA. The RNA fragment must be removed before the fragments are joined. In Saccharomyces cerevisiae, a key player in this process is the structure-specific flap endonuclease,...

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Detalles Bibliográficos
Autores principales: Omer, Sumita, Lavi, Bar, Mieczkowski, Piotr A., Covo, Shay, Hazkani-Covo, Einat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2017
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5677150/
https://www.ncbi.nlm.nih.gov/pubmed/28974572
http://dx.doi.org/10.1534/g3.117.300262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5677150/
https://www.ncbi.nlm.nih.gov/pubmed/28974572
http://dx.doi.org/10.1534/g3.117.300262

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