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Localization of Cdc7 Protein Kinase During DNA Replication in Saccharomyces cerevisiae

DDK, a conserved serine-threonine protein kinase composed of a regulatory subunit, Dbf4, and a catalytic subunit, Cdc7, is essential for DNA replication initiation during S phase of the cell cycle through MCM2-7 helicase phosphorylation. The biological significance of DDK is well characterized, but...

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Detalles Bibliográficos
Autores principales: Rossbach, Daniel, Bryan, D. Suzi, Hesselberth, Jay R., Sclafani, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5677158/
https://www.ncbi.nlm.nih.gov/pubmed/28924058
http://dx.doi.org/10.1534/g3.117.300223