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Squarticles as the nanoantidotes to sequester the overdosed antidepressant for detoxification

The increasing death rate caused by drug overdose points to an urgent demand for the development of novel detoxification therapy. In an attempt to detoxify tricyclic antidepressant overdose, we prepared a lipid nanoemulsion, called squarticles, as the nanoantidote. Squalene was the major lipid matri...

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Detalles Bibliográficos
Autores principales: Chen, Chun-Han, Huang, Tse-Hung, Elzoghby, Ahmed O, Wang, Pei-Wen, Chang, Chia-Wen, Fang, Jia-You
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5677298/
https://www.ncbi.nlm.nih.gov/pubmed/29138563
http://dx.doi.org/10.2147/IJN.S143370