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Squarticles as the nanoantidotes to sequester the overdosed antidepressant for detoxification
The increasing death rate caused by drug overdose points to an urgent demand for the development of novel detoxification therapy. In an attempt to detoxify tricyclic antidepressant overdose, we prepared a lipid nanoemulsion, called squarticles, as the nanoantidote. Squalene was the major lipid matri...
Autores principales: | Chen, Chun-Han, Huang, Tse-Hung, Elzoghby, Ahmed O, Wang, Pei-Wen, Chang, Chia-Wen, Fang, Jia-You |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5677298/ https://www.ncbi.nlm.nih.gov/pubmed/29138563 http://dx.doi.org/10.2147/IJN.S143370 |
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