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Directed differentiation of human pluripotent stem cells to blood-brain barrier endothelial cells

The blood-brain barrier (BBB) is composed of specialized endothelial cells that are critical to neurological health. A key tool for understanding human BBB development and its role in neurological disease is a reliable and scalable source of functional brain microvascular endothelial cells (BMECs)....

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Detalles Bibliográficos
Autores principales: Qian, Tongcheng, Maguire, Shaenah E., Canfield, Scott G., Bao, Xiaoping, Olson, William R., Shusta, Eric V., Palecek, Sean P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5677350/
https://www.ncbi.nlm.nih.gov/pubmed/29134197
http://dx.doi.org/10.1126/sciadv.1701679