Oxidative cyclization of prodigiosin by an alkylglycerol monooxygenase-like enzyme

Prodiginines, tripyrrole alkaloids displaying a wide array of bioactivities, occur as linear and cyclic congeners. Identification of an unclustered biosynthetic gene led to the discovery of the enzyme responsible for catalyzing the regiospecific C–H activation and cyclization of prodigiosin to form...

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Detalles Bibliográficos
Autores principales: de Rond, Tristan, Stow, Parker, Eigl, Ian, Johnson, Rebecca E, Chan, Leanne Jade G, Goyal, Garima, Baidoo, Edward EK, Hillson, Nathan J, Petzold, Christopher J, Sarpong, Richmond, Keasling, Jay D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5677514/
https://www.ncbi.nlm.nih.gov/pubmed/28892091
http://dx.doi.org/10.1038/nchembio.2471

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5677514/
https://www.ncbi.nlm.nih.gov/pubmed/28892091
http://dx.doi.org/10.1038/nchembio.2471

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