Mosaic mutations in blood DNA sequence are associated with solid tumor cancers

Recent understanding of the causal role of blood-detectable somatic protein-truncating DNA variants in leukemia prompts questions about the generalizability of such observations across cancer types. We used the cancer genome atlas exome sequencing (~8000 samples) to compare 22 different cancer pheno...

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Detalles Bibliográficos
Autores principales: Artomov, Mykyta, Rivas, Manuel A., Genovese, Giulio, Daly, Mark J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5677955/
https://www.ncbi.nlm.nih.gov/pubmed/29263833
http://dx.doi.org/10.1038/s41525-017-0025-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5677955/
https://www.ncbi.nlm.nih.gov/pubmed/29263833
http://dx.doi.org/10.1038/s41525-017-0025-4

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