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Heart regeneration in the salamander relies on macrophage-mediated control of fibroblast activation and the extracellular landscape

In dramatic contrast to the poor repair outcomes for humans and rodent models such as mice, salamanders and some fish species are able to completely regenerate heart tissue following tissue injury, at any life stage. This capacity for complete cardiac repair provides a template for understanding the...

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Detalles Bibliográficos
Autores principales: Godwin, J. W., Debuque, R., Salimova, E., Rosenthal, N. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5677961/
https://www.ncbi.nlm.nih.gov/pubmed/29201433
http://dx.doi.org/10.1038/s41536-017-0027-y