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Latent Membrane Protein 1 Is a Novel Determinant of Epstein-Barr Virus Genome Persistence and Reactivation

Epstein-Barr virus (EBV) is a ubiquitous gammaherpesvirus that persistently infects humans, with nearly 95% seropositivity in adults. Infection in differentiating epithelia is permissive, but EBV-associated nasopharyngeal carcinoma (NPC) tumors harbor a clonal and nonproductive latent infection. How...

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Detalles Bibliográficos
Autores principales: Caves, Elizabeth A., Butch, Rachel M., Cook, Sarah A., Wasil, Laura R., Chen, Chen, Di, Yuanpu Peter, Lee, Nara, Shair, Kathy H. Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5677982/
https://www.ncbi.nlm.nih.gov/pubmed/29134204
http://dx.doi.org/10.1128/mSphereDirect.00453-17