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Myeloablation-associated deletion of ORF4 in a human coronavirus 229E infection

We describe metagenomic next-generation sequencing (mNGS) of a human coronavirus 229E from a patient with AML and persistent upper respiratory symptoms, who underwent hematopoietic cell transplantation (HCT). mNGS revealed a 548-nucleotide deletion, which comprised the near entirety of the ORF4 gene...

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Detalles Bibliográficos
Autores principales: Greninger, Alexander L., Pepper, Gregory, Shean, Ryan C., Cent, Anne, Palileo, Isabel, Kuypers, Jane M., Schiffer, Joshua T., Jerome, Keith R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5677986/
https://www.ncbi.nlm.nih.gov/pubmed/29263840
http://dx.doi.org/10.1038/s41525-017-0033-4