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Differential transcriptome regulation by 3,5-T2 and 3′,3,5-T3 in brain and liver uncovers novel roles for thyroid hormones in tilapia

Although 3,5,3′-triiodothyronine (T3) is considered to be the primary bioactive thyroid hormone (TH) due to its high affinity for TH nuclear receptors (TRs), new data suggest that 3,5-diiodothyronine (T2) can also regulate transcriptional networks. To determine the functional relevance of these bioa...

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Detalles Bibliográficos
Autores principales: Olvera, A., Martyniuk, C. J., Buisine, N., Jiménez-Jacinto, V., Sanchez-Flores, A., Sachs, L. M., Orozco, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678081/
https://www.ncbi.nlm.nih.gov/pubmed/29118400
http://dx.doi.org/10.1038/s41598-017-14913-9