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Pumilio-dependent localization of mRNAs at the cell front coordinates multiple pathways required for chemotaxis

Chemotaxis is a specialized form of directed cell migration important for normal development, wound healing, and cancer metastasis. In the social amoeba Dictyostelium discoideum, four signaling pathways act synergistically to maintain directional cell migration. However, it is unknown how these path...

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Detalles Bibliográficos
Autores principales: Hotz, Manuel, Nelson, W. James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678099/
https://www.ncbi.nlm.nih.gov/pubmed/29118357
http://dx.doi.org/10.1038/s41467-017-01536-x