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Engineering Saccharomyces cerevisiae for geranylgeraniol overproduction by combinatorial design
Combinatorial design is an effective strategy to acquire the optimal solution in complex systems. In this study, the combined effects of pathway combination, promoters’ strength fine-tuning, copy numbers and integration locus variations caused by δ-integration were explored in Saccharomyces cerevisi...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678108/ https://www.ncbi.nlm.nih.gov/pubmed/29118396 http://dx.doi.org/10.1038/s41598-017-15005-4 |