The Mammalian Target of Rapamycin and DNA methyltransferase 1 axis mediates vascular endothelial dysfunction in response to disturbed flow

The earliest atherosclerotic lesions preferentially develop in arterial regions experienced disturbed blood flow, which induces endothelial expression of pro-atherogenic genes and the subsequent endothelial dysfunction. Our previous study has demonstrated an up-regulation of DNA methyltransferase 1...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Yun-Peng, Huang, Yi-Tao, Huang, Tse-Shun, Pang, Wei, Zhu, Juan-Juan, Liu, Yue-Feng, Tang, Run-Ze, Zhao, Chuan-Rong, Yao, Wei-Juan, Li, Yi-Shuan, Chien, Shu, Zhou, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678172/
https://www.ncbi.nlm.nih.gov/pubmed/29118325
http://dx.doi.org/10.1038/s41598-017-15387-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678172/
https://www.ncbi.nlm.nih.gov/pubmed/29118325
http://dx.doi.org/10.1038/s41598-017-15387-5

Ejemplares similares