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The Mammalian Target of Rapamycin and DNA methyltransferase 1 axis mediates vascular endothelial dysfunction in response to disturbed flow
The earliest atherosclerotic lesions preferentially develop in arterial regions experienced disturbed blood flow, which induces endothelial expression of pro-atherogenic genes and the subsequent endothelial dysfunction. Our previous study has demonstrated an up-regulation of DNA methyltransferase 1...
Autores principales: | Zhang, Yun-Peng, Huang, Yi-Tao, Huang, Tse-Shun, Pang, Wei, Zhu, Juan-Juan, Liu, Yue-Feng, Tang, Run-Ze, Zhao, Chuan-Rong, Yao, Wei-Juan, Li, Yi-Shuan, Chien, Shu, Zhou, Jing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678172/ https://www.ncbi.nlm.nih.gov/pubmed/29118325 http://dx.doi.org/10.1038/s41598-017-15387-5 |
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