Novel Plasmodium antigens identified via genome-based antibody screen induce protection associated with polyfunctional T cell responses

The development of vaccines against complex intracellular pathogens, such as Plasmodium spp., where protection is likely mediated by cellular immune responses, has proven elusive. The availability of whole genome, proteome and transcriptome data has the potential to advance rational vaccine developm...

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Detalles Bibliográficos
Autores principales: Schussek, Sophie, Trieu, Angela, Apte, Simon H., Sidney, John, Sette, Alessandro, Doolan, Denise L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678182/
https://www.ncbi.nlm.nih.gov/pubmed/29118376
http://dx.doi.org/10.1038/s41598-017-15354-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678182/
https://www.ncbi.nlm.nih.gov/pubmed/29118376
http://dx.doi.org/10.1038/s41598-017-15354-0

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