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Novel Plasmodium antigens identified via genome-based antibody screen induce protection associated with polyfunctional T cell responses
The development of vaccines against complex intracellular pathogens, such as Plasmodium spp., where protection is likely mediated by cellular immune responses, has proven elusive. The availability of whole genome, proteome and transcriptome data has the potential to advance rational vaccine developm...
Autores principales: | Schussek, Sophie, Trieu, Angela, Apte, Simon H., Sidney, John, Sette, Alessandro, Doolan, Denise L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678182/ https://www.ncbi.nlm.nih.gov/pubmed/29118376 http://dx.doi.org/10.1038/s41598-017-15354-0 |
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