Decoy Wnt receptor (sLRP6E1E2)-expressing adenovirus induces anti-fibrotic effect via inhibition of Wnt and TGF-β signaling

Aberrant activation of the canonical Wingless type (Wnt) signaling pathway plays a key role in the development of hypertrophic scars and keloids, and this aberrant activation of Wnt pathway can be a potential target for the development of novel anti-fibrotic agents. In this study, we evaluated the a...

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Detalles Bibliográficos
Autores principales: Lee, Won Jai, Lee, Jung-Sun, Ahn, Hyo Min, Na, Youjin, Yang, Chae Eun, Lee, Ju Hee, Hong, JinWoo, Yun, Chae-Ok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678438/
https://www.ncbi.nlm.nih.gov/pubmed/29118355
http://dx.doi.org/10.1038/s41598-017-14893-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678438/
https://www.ncbi.nlm.nih.gov/pubmed/29118355
http://dx.doi.org/10.1038/s41598-017-14893-w

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