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Decoy Wnt receptor (sLRP6E1E2)-expressing adenovirus induces anti-fibrotic effect via inhibition of Wnt and TGF-β signaling
Aberrant activation of the canonical Wingless type (Wnt) signaling pathway plays a key role in the development of hypertrophic scars and keloids, and this aberrant activation of Wnt pathway can be a potential target for the development of novel anti-fibrotic agents. In this study, we evaluated the a...
Autores principales: | Lee, Won Jai, Lee, Jung-Sun, Ahn, Hyo Min, Na, Youjin, Yang, Chae Eun, Lee, Ju Hee, Hong, JinWoo, Yun, Chae-Ok |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678438/ https://www.ncbi.nlm.nih.gov/pubmed/29118355 http://dx.doi.org/10.1038/s41598-017-14893-w |
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