Effect of Cromakalim Prodrug 1 (CKLP1) on Aqueous Humor Dynamics and Feasibility of Combination Therapy With Existing Ocular Hypotensive Agents

PURPOSE: Cromakalim prodrug 1 (CKLP1) is a water-soluble ATP-sensitive potassium channel opener that has shown ocular hypotensive properties in ex vivo and in vivo experimental models. To determine its mechanism of action, we assessed the effect of CKLP1 on aqueous humor dynamics and in combination...

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Detalles Bibliográficos
Autores principales: Roy Chowdhury, Uttio, Rinkoski, Tommy A., Bahler, Cindy K., Millar, J. Cameron, Bertrand, Jacques A., Holman, Bradley H., Sherwood, Joseph M., Overby, Darryl R., Stoltz, Kristen L., Dosa, Peter I., Fautsch, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2017
Materias:
Glaucoma
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678549/
https://www.ncbi.nlm.nih.gov/pubmed/29114841
http://dx.doi.org/10.1167/iovs.17-22538

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678549/
https://www.ncbi.nlm.nih.gov/pubmed/29114841
http://dx.doi.org/10.1167/iovs.17-22538

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