Optimization and characterization of spray-dried IgG formulations: a design of experiment approach

BACKGROUND: The purpose of the present study is to optimize a spray-dried formulation as a model antibody regarding stability and aerodynamic property for further aerosol therapy of this group of macromolecules. METHOD: A three-factor, three-level, Box-Behnken design was employed milligrams of Cyste...

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Detalles Bibliográficos
Autores principales: Faghihi, Homa, Najafabadi, Abdolhosein Rouholamini, Vatanara, Alireza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678550/
https://www.ncbi.nlm.nih.gov/pubmed/29065930
http://dx.doi.org/10.1186/s40199-017-0187-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678550/
https://www.ncbi.nlm.nih.gov/pubmed/29065930
http://dx.doi.org/10.1186/s40199-017-0187-8

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